I run bowl.science, an online Science Bowl tournament platform. It’s a side project, but it’s real production: the DOE Office of Science uses it for their Science Bowl competitions. When a tournament is happening, the app needs to work. There’s no “we’ll fix it in the next sprint.”
My friend Alexa is a graphic designer. Last week I asked her what percentage of her time she spends on meta-design. She asked me what that meant.
Update, August 2026: I no longer stand behind this approach. The model below measures how surprising a user’s silence is against their own history, and in production that turned out to flag the users least likely to leave. I’ve written up what went wrong and what replaced it in Churn Risk Is a Conditional Rate. The original post is left as written.
A Motivating Example
We were studying how microglia affect neuronal networks using a standard imaging experiment: 3 mice, 3 coverslips per condition, about 20 neurons measured per coverslip. Our question: Does LPS activation significantly increase PNA signal?
A while back, I wrote a short piece about planning scientific projects for New Science. The article explores systematic approaches to identifying impactful research questions and structuring PhD projects for maximum scientific contribution.